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|Title: ||Pharmacognostic Studies and Antioxidant Properties of the Leaves of Solanum macrocarpon.|
|Authors: ||Komlaga, G.|
Sam, G. H.
Dickson, R. A.
Mensah, M. L. K.
Fleischer, T. C.
|Keywords: ||Solanum macrocarpon|
|Issue Date: ||2014|
|Publisher: ||Journal Pharmaceutical Science & Research|
|Citation: ||Journal Pharmaceutical Science & Research, Vol. 6(1), 2014, 1 - 4|
|Abstract: ||The leaves of Solanum macrocarpon (Solanaceae) was evaluated for its pharmacognostic characteristics and antioxidant properties.
Microscopic studies showed the presence of both anomocytic and anisocytic types of stomata on both the upper and the lower
epidermis, unicellular and branched clothing trichomes as well as glandular trichomes with unicellular stalk and multicellular
heads. The leaf is dorsiventral with the mesophyll cells containing abundant prismatic calcium oxalate crystals. The midrib showed
a crescent-shape and bicollateral vascular bundle. Microscopic evaluation established Stomatal index as 11.59±0.63 and
18.69±0.84 for the upper and lower surfaces respectively. The palisade ratio, the vein islet and vein-let termination numbers were
determined as 6.22±0.36, 9.09±0.64 and 9.02±0.53 respectively. Physicochemical evaluation yielded extractive values of
1.33±0.33, 4.65±0.66, 8.66±0.32 and 7.34±0.25 for petroleum ether, ethyl acetate, ethanol (95%) and water respectively. Total
Ash, Water soluble, Acid insoluble Ash were 13.96±0.06, 6.86±0.16 and 2.20±0.09 respectively. Basic phytochemical screening
revealed the presence of tannins, flavonoids and alkaloids. The alcoholic extract showed radical scavenging activity with IC50 of
2.42mg/ml. The pharmacognostic standards and the antioxidant activity of the leaf of S. macrocarpon have been established. The
pharmacognostic standards are essential for proper identification of the plant.|
|Description: ||An article published by Journal Pharmaceutical Science & Research, Vol. 6(1), 2014, 1 - 4|
|Appears in Collections:||College of Health Sciences|
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