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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/11213

Title: Phytoconstituents, antimicrobial and antioxidant properties of the leaves of Persea americana Mill cultivated in Ghana
Authors: Boadi, Nathaniel Owusu
Saah, Selina Ama
Mensah, John Kenneth
Badu, Mercy
Addai-Arhin, Sylvester
Mensah, Michael Baah
Keywords: Persea americana
Antioxidant
Antimicrobial
Phytochemical screening
Minimum inhibitory concentration
Issue Date: 25-Sep-2015
Publisher: Journal of Medicinal Plants Research
Citation: Journal of Medicinal Plants Research; Vol. 9(36), pp. 933- 939, 25 September, 2015; DOI: 10.5897/JMPR2015.5902; Article Number: B13A36455396, ISSN 1996-0875
Abstract: The leaves of Persea americana are widely used for ethno-medicinal purposes worldwide. This study assessed the antimicrobial and antioxidant activities of the methanol, ethyl acetate, chloroform and petroleum ether leaves extracts of P. americana. Extracts displayed variable antimicrobial activities that were microorganism-specific. The methanolic extract displayed the most potent antimicrobial activities with the largest zones of inhibition (0-1.8 mm) in the agar diffusion assay and with the lowest minimum inhibitory concentration (MIC) in the broth dilution assay against a panel of microorganisms that included Bacillus subtilis, Escherichia coli, Salmonella typhi, Streptococcus aureus, Pseudomonas aeruginosa and Candida albicans. The ethyl acetate extract exhibited the most potent antioxidant potential with the lowest EC50 of 4.15x10-30 g/ml for the peroxide radical scavenging activities. The data supports the ethnomedicinal use of the leaves of P. americana for the management of infections and for other symptoms whose etiology may be linked to oxidative stress.
Description: An article published by Journal of Medicinal Plants Research; Vol. 9(36), pp. 933- 939, 25 September, 2015; DOI: 10.5897/JMPR2015.5902; Article Number: B13A36455396, ISSN 1996-0875
URI: http://hdl.handle.net/123456789/11213
ISSN: 1996-0875
Appears in Collections:College of Science

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