Research Articles >
College of Health Sciences >
Please use this identifier to cite or link to this item:
|Title: ||Phytochemical characterization and in vitro wound healing activity of leaf extracts from Combretum mucronatum Schum. &Thonn.: Oligomeric procyanidins as strong inductors of cellular differentiation|
|Authors: ||Kisseih, E.|
|Issue Date: ||Mar-2015|
|Publisher: ||Journal of Ethnopharmacology|
|Citation: ||Journal of Ethnopharmacology, 2015|
|Abstract: ||Ethnopharmacological relevance: Leaves from Combretum mucronatum Schum. &Thonn. are traditionally used or wound healing in Western Africa. Aqueous and hydro alcoholic extracts of the dried leaves
recently have been shown to stimulate viability of human keratinocytes and dermal fibroblasts.
Aim of the study: Phytochemical characterization of the herbal material,development of a validated HPLC
methodology for quality control,and pin pointing the under lying pharmacological mechanism under
in vitro conditions to understand the impact of C. mucronatum extracts on human skin cells.
Materials and methods: Extracts obtained from the leaves from C. mucronatum by using solvents with
different polarities(petrol ether,dichloromethane,ethanol–water5 0%,water)were investigated
concerning phytochemical composition by GC–MS, LC–MS and in part after fraction at ion and isolation
of purified compounds.For quality control of the herbal material an ICH-2 validated UHPLC method was
developed for quantification of the lead ...................|
|Description: ||An article published by Journal of Ethnopharmacology, 2015|
|Appears in Collections:||College of Health Sciences|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.