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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/11883

Title: High prevalence of multidrug-resistant tuberculosis among patients with rifampicin resistance using GeneXpert Mycobacterium tuberculosis/rifampicin in Ghana
Authors: Boakye-Appiah, Justice K.
Steinmetz, Alexis R.
Pupulampu, Peter
Ofori-Yirenkyi, Stephen
Phillips, Richard O.
et. al
Keywords: GeneXpert GeneXpert MTB/RIF Multidrug-resistant tuberculosis Xpert MTB/RIF
Issue Date: 8-Mar-2016
Publisher: Elsevier Ltd.
Citation: Elsevier Ltd 5 ( 2 0 1 6 ) 2 2 6 –2 3 0
Abstract: Objective/Background: Drug-resistant strains of tuberculosis (TB) represent a major threat to global TB control. In low- and middle-income countries, resource constraints make it difficult to identify and monitor cases of resistance using drug susceptibility testing and culture. Molecular assays such as the GeneXpert Mycobacterium tuberculosis/rifampicin may prove to be a cost-effective solution to this problem in these settings. The objective of this study is to evaluate the use of GeneXpert in the diagnosis of pulmonary TB since it was introduced into two tertiary hospitals in Ghana in 2013. Methods: A 2-year retrospective audit of clinical cases involving patients who presented with clinically suspected TB or documented TB not improving on standard therapy and had samples sent for GeneXpert testing.
Description: An article published by Elsevier Ltd.
URI: http://hdl.handle.net/123456789/11883
Appears in Collections:College of Health Sciences

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