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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/12082

Title: Clinical Evaluation of the Safety and Effectiveness of Adutwumwaa Malamix: A Polyherbal Product for the Treatment of Uncomplicated Malaria in Ghana
Authors: Tetteh, Andrews W.
Mensah, Merlin L.
Boadu, Kwame O.
Thomford, Kwesi P.
Agyemang, Michael O.
Annan, Kofi
Dickson, Rita A.
Mensah, Abraham Y.
Amposah, Isaac K.
Ekuadzi, Edmund
Owusu-Ansah, Emmanuel D. J
Keywords: Adutwumwaa malamix
Anthocleista nobilis
Phyllanthus fratenus
polyherbal antimalaria
safety and effectiveness
Vitex grandifolia
Issue Date: Jul-2017
Publisher: Journal of Applied Pharmaceutical Science
Citation: Journal of Applied Pharmaceutical Science, Vol. 7 (07), pp. 040-045,
Abstract: Antimalarial medications remain one of the major interventional tools for the global malaria control efforts. One of the most popular Ghanaian herbal antimalarial agent is the product sold under the trade name ‘Adutwumwaa malamix’. This product is registered with the Food and Drugs Authority (FDA) of Ghana as treatment of uncomplicated malaria. In this study, the safety and effectiveness of the product ‘Adutwumwaa malamix’ for the treatment of uncomplicated malaria was clinically evaluated based on disease-oriented and patient-oriented evidence. A total of 42 subjects were recruited for the study. Complete cure was achieved for 35 (83.33%) of participants by day 7 of the study. Partial efficacy was also achieved for 7 (16.66%) of subjects. Patient reported symptoms such fever, chills and abdominal pains were also significantly improved by day 7 and absent by day 28. The safety parameters assessed did not show any clinically significant change among the study population during treatment. The outcome of the study indicates that the Ghanaian herbal antimalarial agent ‘Adutwumwaa malamix’ may be an effective herbal treatment for the management of uncomplicated malaria.
Description: This article is published in Journal of Applied Pharmaceutical Science and also available at DOI: 10.7324/JAPS.2017.70706
URI: 10.7324/JAPS.2017.70706
Appears in Collections:College of Health Sciences

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