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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/12355

Title: Heavy metals and metalloid accumulation in livers and kidneys of wild rats around gold-mining communities in Tarkwa, Ghana
Authors: Bortey-Sam, Nesta
Nakayama, Shouta M. M.
Ikenaka, Yoshinori
Akoto, Osei
Baidoo, Elvis
Mizukawa, Hazuki
Ishizuka, Mayumi
Keywords: Wild rats
heavy metal
metalloid
liver
kidney
Ghana
Issue Date: May-2016
Publisher: Journal of Environmental Chemistry and Ecotoxicology
Citation: Journal of Environmental Chemistry and Ecotoxicology, Vol. 8(7), pp. 58-68
Abstract: Previous studies revealed high levels of metals in soils, drinking water, foodstuffs and food animals in several communities in Tarkwa, Ghana. Therefore wild rats were trapped from 16 communities in Tarkwa to estimate the environmental pollution state of metals; determine differences in sex in metal accumulation; and assess the potential risks involved. Concentrations of arsenic (As), cadmium (Cd), cobalt (Co), chromium (Cr), copper (Cu), manganese (Mn), nickel (Ni), lead (Pb) and zinc (Zn) were measured in the livers and kidneys of wild rats; and livers accumulated higher levels of As than kidneys but the reverse was for Cd and Pb. In both organs, As, Cd and Zn levels were higher in female than the male rats. There was a strong positive correlation between body weight and Cd concentrations in livers and kidneys of wild rats which reflects a mechanism of protection against the development of osteopenia, although a biological effect remains a concern. Pb levels in the kidneys could cause intra nuclear inclusion bodies and karyocytomegaly in the proximal tubular cells in 29% of wild rats in Tarkwa and structural and functional kidney damage in 6%. Concentrations of As in kidneys of these wild rats could cause glomerular swelling in 9% of rats. Principal component analysis of the results showed that wild rats in Tarkwa were exposed to heavy metals and a metalloid through borehole drinking water and soils.
Description: This article is published in Journal of Environmental Chemistry and Ecotoxicology and also available at DOI:10.5897/JECE2016.0374
URI: :10.5897/JECE2016.0374
http://hdl.handle.net/123456789/12355
Appears in Collections:College of Science

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