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Title: | Phytochemical screening and in vitro antioxidant and antimicrobial activities of the extracts of the stem-bark of Psydrax peruviana |
Authors: | Akoto, Clement Osei Acheampong, Akwasi Boakye, Yaw Duah Takyi, Samuel Garba, Rukaya |
Keywords: | Psydrax peruviana, antimicrobial, antioxidant phytochemical, assay in-vitro |
Issue Date: | 2019 |
Publisher: | AkiNik Publications |
Citation: | Journal of Medicinal Plants Studies 2019; 7(5): 28-34 |
Abstract: | The stem-bark of Psydrax peruviana is used in folkloric medicine in the treatment of gonorrhoea and
syphilis. In this study, methanol and hexane extracts of P. peruviana were evaluated for antimicrobial
and antioxidant properties. Phytochemical screening, antimicrobial (agar and broth dilution method) and
antioxidant (total antioxidant capacity (TAC), DPPH and H2O2 scavenging) assays were carried out on
the extracts. The hexane and methanol extracts showed antimicrobial activity against test organisms with
MICs ranging from 1.25 – 20 mg/mL. The IC50 values for methanol and hexane extracts in the DPPH and
H2O2 assays were 12.20 and 24.26 µg/mL and 1143.0 and 2872.0 µg/mL, respectively. The TAC
(gAAE/100 g) for methanol and hexane extracts were 21.563 and 17.389 g, respectively. The
phytochemical investigation revealed the presence of plant secondary metabolites such as tannins,
flavonoid, glycosides, terpenoids, steroids, carotenoids and saponins. These findings provide scientific
justification for the use of P. peruviana in various traditional medicines, for the treatment and
management of diseases. |
Description: | An article published by AkiNik Publications |
URI: | http://hdl.handle.net/123456789/12387 |
Appears in Collections: | College of Science
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