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Title: | Hematological Differences among Malaria Patients in Rural and Urban Ghana |
Authors: | Iqbal, Shareen A. Botchway, Felix Badu, Kingsley Wilson, Nana O. Dei-Adomakoh, Yvonne et. al |
Keywords: | anemia global health Plasmodium falciparum malaria hematological parameters Ghana exposome |
Issue Date: | 17-Jun-2016 |
Publisher: | Oxford University Press |
Citation: | Journal of Tropical Pediatrics, 2016, 62, 477–486 doi: 10.1093/tropej/fmw038., Hematological Differences among Malaria Patients |
Abstract: | Background: Scarce studies have addressed hematological differences of malaria in urban and rural
regions.
Methods: Full or complete blood cell counts from 46 and 75 individuals (age range from<1 to 92
years) with uncomplicated malaria infection living in urban (Accra) and rural (Dodowa) Ghana, respectively,
were assessed. Sickle cell trait and patients were excluded from the study.
Results: Between overall groups, patients from Accra had significantly lower parasite count (p <
0.0001) and granulocyte number (p ¼ 0.026). Children in Accra had a significantly lower parasitemia
(p ¼ 0.0013), hemoglobin (p ¼ 0.0254), platelet count (p ¼ 0.0148) and red blood cell levels
(p ¼ 0.0080) when compared with the children of Dodowa. In adults, mean cell hemoglobin (p ¼ 0.0086) and parasite count (p < 0.0001) were significantly higher in Dodowa.
Conclusion: These results indicate that children living in urban setting may experience a greater anemic
effect to malaria as compared with those living in a rural settin |
Description: | An article published by Oxford University Press and also available at doi: 10.1093/tropej/fmw038 |
URI: | http://hdl.handle.net/123456789/12488 |
Appears in Collections: | College of Science
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