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|Title: ||Hematological Differences among Malaria Patients in Rural and Urban Ghana|
|Authors: ||Iqbal, Shareen A.|
Wilson, Nana O.
Plasmodium falciparum malaria
|Issue Date: ||17-Jun-2016|
|Publisher: ||Oxford University Press|
|Citation: ||Journal of Tropical Pediatrics, 2016, 62, 477–486 doi: 10.1093/tropej/fmw038., Hematological Differences among Malaria Patients|
|Abstract: ||Background: Scarce studies have addressed hematological differences of malaria in urban and rural
Methods: Full or complete blood cell counts from 46 and 75 individuals (age range from<1 to 92
years) with uncomplicated malaria infection living in urban (Accra) and rural (Dodowa) Ghana, respectively,
were assessed. Sickle cell trait and patients were excluded from the study.
Results: Between overall groups, patients from Accra had significantly lower parasite count (p <
0.0001) and granulocyte number (p ¼ 0.026). Children in Accra had a significantly lower parasitemia
(p ¼ 0.0013), hemoglobin (p ¼ 0.0254), platelet count (p ¼ 0.0148) and red blood cell levels
(p ¼ 0.0080) when compared with the children of Dodowa. In adults, mean cell hemoglobin (p ¼ 0.0086) and parasite count (p < 0.0001) were significantly higher in Dodowa.
Conclusion: These results indicate that children living in urban setting may experience a greater anemic
effect to malaria as compared with those living in a rural settin|
|Description: ||An article published by Oxford University Press and also available at doi: 10.1093/tropej/fmw038|
|Appears in Collections:||College of Science|
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