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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/12512

Title: Human Parvovirus 4 in Nasal and Fecal Specimens from Children, Ghana
Authors: Drexler, Jan Felix
Reber, Ulrike
Muth, Doreen
Herzog, Petra
Annan, Augustina
et. al
Issue Date: Oct-2012
Publisher: Emerging Infectious Diseases
Citation: Emerging Infectious Diseases. Vol. 18, No. 10, October 2012. DOI: http://dx.doi.org/10.3201/eid1810.111373
Abstract: Human parvovirus 4 (PARV4; human partetravirus) is a single-stranded DNA virus discovered in 2005 (1). PARV4 has been detected in persons at risk for parenteral infections, suggesting blood-borne transmission (2,3) although other transmission routes have not been ruled out. Studies in northern Europe demonstrated a high prevalence of antibodies against PARV4 in injection drug users, persons co-infected with HIV and hepatitis C virus, and persons with hemophilia who were exposed to nonvirally inactivated clotting factors; however, antibodies were not detected in the general population (4,5). In contrast, PARV4 seroprevalence was 25%–37% in adults in the Democratic Republic of Congo, Cameroon, and Burkina Faso who were not infected with HIV and hepatitis C virus. (6). PARV4 DNA was detected in blood of 8.6% of children 15 or 24 months of age in Ghana (7). There was no history of exposure to multiple-use needles or blood transfusion in any of these children. These data suggested alternative modes of PARV4 transmission in countries in Africa.
Description: An article published by Emerging Infectious Diseases and also available at DOI: http://dx.doi.org/10.3201/eid1810.111373
URI: http://hdl.handle.net/123456789/12512
Appears in Collections:College of Science

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