Research Articles >
College of Science >
Please use this identifier to cite or link to this item:
|Title: ||Human Parvovirus 4 in Nasal and Fecal Specimens from Children, Ghana|
|Authors: ||Drexler, Jan Felix|
|Issue Date: ||Oct-2012|
|Publisher: ||Emerging Infectious Diseases|
|Citation: ||Emerging Infectious Diseases. Vol. 18, No. 10, October 2012. DOI: http://dx.doi.org/10.3201/eid1810.111373|
|Abstract: ||Human parvovirus 4 (PARV4; human partetravirus) is
a single-stranded DNA virus discovered in 2005 (1).
PARV4 has been detected in persons at risk for parenteral
infections, suggesting blood-borne transmission (2,3)
although other transmission routes have not been ruled out.
Studies in northern Europe demonstrated a high prevalence
of antibodies against PARV4 in injection drug users,
persons co-infected with HIV and hepatitis C virus, and
persons with hemophilia who were exposed to nonvirally
inactivated clotting factors; however, antibodies were not
detected in the general population (4,5).
In contrast, PARV4 seroprevalence was 25%–37% in
adults in the Democratic Republic of Congo, Cameroon,
and Burkina Faso who were not infected with HIV and
hepatitis C virus. (6). PARV4 DNA was detected in blood
of 8.6% of children 15 or 24 months of age in Ghana (7).
There was no history of exposure to multiple-use needles
or blood transfusion in any of these children. These data
suggested alternative modes of PARV4 transmission in
countries in Africa.|
|Description: ||An article published by Emerging Infectious Diseases and also available at DOI: http://dx.doi.org/10.3201/eid1810.111373|
|Appears in Collections:||College of Science|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.