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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/13426

Title: Prevalence and Prognostic Features of ECG Abnormalities in Acute Stroke: Findings From the SIREN Study Among Africans
Authors: Adeoye, Abiodun M.
Ogah, Okechukwu S.
Ovbiagele, Bruce
Akinyemi, Rufus
Shidali, Vincent
Agyekum, Francis
Akinyemi, Aje
Oladimeji, Adebayo
Akinyemi, Joshua O.
Kolo, Philip
Sarfo, Fred Stephen...et.al.
Issue Date: 2017
Publisher: Epidemiology Faculty Publications
Citation: Adeoye, Abiodun M.; Ogah, Okechukwu S.; Ovbiagele, Bruce; Akinyemi, Rufus; Shidali, Vincent; Agyekum, Francis; Aje, Akinyemi; Adebayo, Oladimeji; Akinyemi, Joshua O.; Kolo, Philip; Appiah, Lambert Tetteh; Iheonye, Henry; Kelechukwu, Uwanuruochi; Ganiyu, Amusa; Olunuga, Taiwo O.; Akpa, Onoja; Olagoke, Ojo Olakanmi; Sarfo, Fred Stephen; Wahab, Kolawole; Olowookere, Samuel; Fakunle, Adekunle; Akpalu, Albert; Adebayo, Philip B.; Nkromah, Kwadwo; Yaria, Joseph; Ibinaiye, Philip; Ogbole, Godwin; Olumayowa, Aridegbe; Lakoh, Sulaiman; Calys-Tagoe, Benedict; and Arnett, Donna K., "Prevalence and Prognostic Features of ECG Abnormalities in Acute Stroke: Findings From the SIREN Study Among Africans" (2017). Epidemiology Faculty Publications. 44. https://uknowledge.uky.edu/epidemiology_facpub/44
Abstract: Background—Africa has a growing burden of stroke with associated high morbidity and a 3- year fatality rate of 84%. Cardiac disease contributes to stroke occurrence and outcomes, but the precise relationship of abnormalities as noted on a cheap and widely available test, the electrocardiogram (ECG), and acute stroke outcomes has not been previously characterized in Africans. We assessed the prevalence and prognoses of various ECG abnormalities among African acute stroke patients encountered in a multisite, cross-national epidemiologic study. Methods—We included 890 patients from Nigeria and Ghana with acute stroke who had 12-lead ECG recording within first 24 hours of admission and stroke classified based on brain CT scan or MRI. Stroke severity at baseline was assessed using the Stroke levity scale (SLS), while onemonth outcome was assessed using the modified Rankin scale (mRS). Results—Patients mean age was 58.4 (±13.4) years, 490 were male (55%) and 400(45%) females, 65.5% had ischemic stroke, and 85.4% had at least one ECG abnormality. Women were significantly more likely to have atrial fibrillation, or left ventricular hypertrophy (LVH) with or without strain pattern. Compared to ischemic stroke patients, hemorrhagic stroke patients were less likely to have atrial fibrillation (1.0% vs. 6.7%, p=0.002), but more likely to have LVH (64.4% vs. 51.4%, p=0.004). Odds of severe disability or death at one month was higher with severe stroke (AOR: 2.25; 95% CI :1.44–3.50), or atrial enlargement (AOR: 1.45; CI:1.04–2.02). Conclusions—About four in five acute stroke patients in this African cohort had evidence of a baseline ECG abnormality, but presence of any atrial enlargement was the only independent ECG predictor of death or disability.
Description: An article published by Adeoye, Abiodun M.; Ogah, Okechukwu S.; Ovbiagele, Bruce; Akinyemi, Rufus; Shidali, Vincent; Agyekum, Francis; Aje, Akinyemi; Adebayo, Oladimeji; Akinyemi, Joshua O.; Kolo, Philip; Appiah, Lambert Tetteh; Iheonye, Henry; Kelechukwu, Uwanuruochi; Ganiyu, Amusa; Olunuga, Taiwo O.; Akpa, Onoja; Olagoke, Ojo Olakanmi; Sarfo, Fred Stephen; Wahab, Kolawole; Olowookere, Samuel; Fakunle, Adekunle; Akpalu, Albert; Adebayo, Philip B.; Nkromah, Kwadwo; Yaria, Joseph; Ibinaiye, Philip; Ogbole, Godwin; Olumayowa, Aridegbe; Lakoh, Sulaiman; Calys-Tagoe, Benedict; and Arnett, Donna K., "Prevalence and Prognostic Features of ECG Abnormalities in Acute Stroke: Findings From the SIREN Study Among Africans" (2017). Epidemiology Faculty Publications. 44. https://uknowledge.uky.edu/epidemiology_facpub/44
URI: http://hdl.handle.net/123456789/13426
Appears in Collections:College of Health Sciences

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