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Title: | High Prevalence of non-adherence to antiretroviral therapy among undisclosed HIV-infected children in Ghana |
Authors: | Nichols, Justin S. Kyriakides, Tassos C. Antwi, Sampson Renner, Lorna Lartey, Margaret Seaneke, Obedia A. Obeng, Raphael Catlin, Ann C. Gan, Geliang R., Nancy |
Keywords: | Adherence Sub-Saharan Africa Antiretroviral therapy Pediatrics |
Issue Date: | 2019 |
Publisher: | HHS Public Access |
Abstract: | Adherence to antiretroviral therapy (ART) remains one of the greatest obstacles in pediatric HIV care. We sought to determine the prevalence of adherence to ART among undisclosed HIV-infected children and adolescents in Ghana. We analyzed baseline data from HIV-infected children and adolescents aged 7 to 18 years old enrolled in the SANKOFA Pediatric HIV disclosure intervention study in Ghana. Antiretroviral medication adherence was measured using caregiver 3-day recall; child 3-day recall; and pharmacy records for antiretroviral time-to-refill. Four hundred and twenty child-caregiver dyads were enrolled from January 2013 to June 2016. The median adherence (interquartile range), as measured by time-to-refill, was 93.2% (68.0% – 100.0%). However, only 47.5% of children had ≥95% adherence (“good adherence”) using time-to-refill data. |
Description: | This article is published in HHS Public Access and also available at doi:10.1080/09540121.2018.1524113. |
URI: | http://hdl.handle.net/123456789/13536 |
ISSN: | 10.1080/09540121.2018.1524113. |
Appears in Collections: | College of Agric and Natural Resources
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