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|Title: ||Peritoneal Dialysis as a Mode of Treatment for Acute Kidney Injury in Sub-Saharan Africa|
|Authors: ||Callegari, John|
W. Levin, Nathan
|Keywords: ||Acute kidney injury|
|Issue Date: ||2013|
|Publisher: ||Blood Purification|
|Abstract: ||Background: Developing sustainable treatment programs
for kidney failure in most countries of sub-Saharan Africa
continues to remain an imposing challenge. While longterm
renal replacement therapies in end-stage renal disease
appear beyond national financial capabilities, there exist opportunities
for a short-term and affordable treatment of
acute kidney injury (AKI). Peritoneal dialysis (PD) is an effective
and simpler modality compared to hemodialysis (HD)
and can be performed without the need for machinery or
electricity, making it an ideal choice in a low-resource setting.
Methods: Since cost of treatment is the major obstacle,
the goal is to develop a program that is cost effective. Developing
an HD program requires a large capital investment by
the hospital, needing water treatment systems and machinery
and providing for their ongoing repair and maintenance.
Gravity-driven PD is a simple, effective modality and can be
performed in low-resource locales. Results: In a pediatric
program that we started in the Komfo Anokye Teaching Hos- pital in Kumasi, Ghana, 28 patients have been treated with
PD for AKI so far. Half of them were treated successfully and
were discharged having fully recovered kidney function.
Seven patients (25%) were determined to have end-stage
renal disease, whereas 7 others (25%) died during hospitalization.
In these cases, late presentation for dialysis may have
contributed to the inability to recover. Conclusion: For individuals
and governments alike, who are concerned about
the cost of providing or paying for dialysis, using PD to treat
AKI is an effective and simpler modality compared to HD and
can be performed without the need for machinery or electricity,
making it an ideal choice in a low-resource setting.|
|Description: ||This article is published in Blood Purification and also available at DOI: 10.1159/000356627|
|Appears in Collections:||College of Health Sciences|
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