Antimicrobial properties of metal piperidine dithiocarbamate complexes against Staphylococcus aureus and Candida albicans
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2021
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Abstract
In this study, a series of metal piperidine dithiocarbamate complexes (M = Zn, Cu, Co, Fe, Ni, Bi and Ag) were synthesized and characterized using microelemental, 1 HNMR, mass spectrometry and FT-IR analyses. Antimicrobial properties of the complexes were tested against Staphylococcus aureus and Candida albicans in a 96-well plate, using the broth dilution assay. The antimicrobial activity of the complexes was in the order Zn > Co > Cu > Ag = Bi = Ni > Fe against Staphylococcus aureus and Co > Zn > Fe > Ag = Bi = Cu = Ni against Candida albicans. The results indicate that the complexes were effective against the microorganisms at high concentrations.
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This article is published by Elsevier and is also available at https://doi.org/10.1016/j.sciaf.2021.e00846
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Scientific African 12 (2021) e00846