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Title: | Stroke in Africa: profile, progress, prospects and priorities |
Authors: | Akinyemi, Rufus O. Ovbiagele, Bruce Adeniji, Olaleye A. Sarfo, Fred Stephen Abd- Allah, Foad Adoukonou, Thierry Ogah, Okechukwu S. Naidoo, Pamela Damasceno, Albertino Walker, Richard W. Ogunniyi, Adesola Kalaria, Rajesh N. Owolabi, Mayowa O. |
Issue Date: | Sep-2021 |
Publisher: | Nature Reviews Neurology |
Citation: | Nature Reviews Neurology, 17(Suppl. 1):1-23 |
Abstract: | Abstract | Stroke is a leading cause of disability, dementia and death worldwide. Approximately
70% of deaths from stroke and 87% of stroke- related disability occur in low- income and middleincome
countries. At the turn of the century, the most common diseases in Africa were
communicable diseases, whereas non- communicable diseases, including stroke, were considered
rare, particularly in sub- Saharan Africa. However, evidence indicates that, today, Africa could
have up to 2–3- fold greater rates of stroke incidence and higher stroke prevalence than western
Europe and the USA. In Africa, data published within the past decade show that stroke has an
annual incidence rate of up to 316 per 100,000, a prevalence of up to 1,460 per 100,000 and a
3- year fatality rate greater than 80%. Moreover, many Africans have a stroke within the fourth to
sixth decades of life, with serious implications for the individual, their family and society. This age
profile is particularly important as strokes in younger people tend to result in a greater loss of
self- worth and socioeconomic productivity than in older individuals. Emerging insights from
research into stroke epidemiology, genetics, prevention, care and outcomes offer great prospects
for tackling the growing burden of stroke on the continent. In this article, we review the unique
profile of stroke in Africa and summarize current knowledge on stroke epidemiology, genetics,
prevention, acute care, rehabilitation, outcomes, cost of care and awareness. We also discuss
knowledge gaps, emerging priorities and future directions of stroke medicine for the more than
1 billion people who live in Africa. |
Description: | This article is published by Nature Reviews Neurology and is also available at https://doi.org/10.1038/
s41582-021-00542-4 |
URI: | 10.1038/ s41582-021-00542-4 http://hdl.handle.net/123456789/15775 |
Appears in Collections: | College of Health Sciences
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