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|Title: ||Hispidulin and other Constituents of Scoparia Dulcis Linn|
|Authors: ||Osei-Safo, D.|
Chama, M. A.
|Keywords: ||Scoparia dulcis|
|Issue Date: ||2009|
|Publisher: ||Journal of Science and Technology|
|Citation: ||Journal of Science and Technology, Vol. 29, No. 2, Aug., 2009, pp 7-15|
|Abstract: ||Phytochemical investigation of the ethanol extract of the whole plant of Scoparia dulcis, has resulted in the isolation of 4, 5, 7-trihydroxy-6-methoxyflavone, commonly called hispidulin and a steroidal glycoside, β-sitosterol-β-D-glucoside. This is the first isolation of the two compounds from S. dulcis. Also isolated and characterized were the previously reported 6-methoxybenzoxazolinone, friedelan-3-one and scopadulcic acid B. Structural elucidation was done on the basis of spectroscopic data interpretations (IR, UV, NMR and EIMS). Using the Tetrazolium-based colorimetric selective assay, hispidulin was found to be inactive against HIV-1/IIIB in MT-4 cells whereas the same test on the aqueous extract of the plant was positive.|
|Description: ||Article published in the Journal of Science and Technology, Vol. 29, No. 2, Aug., 2009, pp 7-15|
|Appears in Collections:||Journal of Science and Technology 2000-|
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