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|Title: ||Comparison of latex agglutination, wet preparation, and culture for the detection of Trichomonas vaginalis|
|Authors: ||Adu-Sarkodie, Yaw|
Opoku, B. K.
Danso, K. A.
Weiss, H. A.
|Issue Date: ||18-Jan-2004|
|Publisher: ||Group BMJ|
|Abstract: ||Objectives: To compare the performance of three diagnostic methods for Trichomonas vaginalis
infection—latex agglutination, saline wet mount, and culture.
Methods: Vaginal swabs from 3807 women attending antenatal clinics were tested for the presence of T
vaginalis by latex agglutination. All positives and the following two negatives were tested by wet
preparation and culture.
Results: The prevalence of infection by latex agglutination was 5.4%. Using an expanded gold standard
based on the wet mount and culture results, the sensitivity of the latex agglutination test was 98.8% (95% CI
95.9 to 99.9) and specificity was 92.1 (89.2 to 94.5). The kappa index for test agreement was 0.93 for
latex and culture and 0.88 for latex and wet preparation.
Conclusion: The latex agglutination test is a highly sensitive test for detecting T vaginalis infection. It is a simple rapid test and has the potential for use in screening and diagnostic settings.|
|Description: ||This article was published by Group BMJ in 2004.|
|Appears in Collections:||College of Health Sciences|
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