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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/5154

Title: Comparison of latex agglutination, wet preparation, and culture for the detection of Trichomonas vaginalis
Authors: Adu-Sarkodie, Yaw
Opoku, B. K.
Danso, K. A.
Weiss, H. A.
Mabey, D.
Issue Date: 18-Jan-2004
Publisher: Group BMJ
Abstract: Objectives: To compare the performance of three diagnostic methods for Trichomonas vaginalis infection—latex agglutination, saline wet mount, and culture. Methods: Vaginal swabs from 3807 women attending antenatal clinics were tested for the presence of T vaginalis by latex agglutination. All positives and the following two negatives were tested by wet preparation and culture. Results: The prevalence of infection by latex agglutination was 5.4%. Using an expanded gold standard based on the wet mount and culture results, the sensitivity of the latex agglutination test was 98.8% (95% CI 95.9 to 99.9) and specificity was 92.1 (89.2 to 94.5). The kappa index for test agreement was 0.93 for latex and culture and 0.88 for latex and wet preparation. Conclusion: The latex agglutination test is a highly sensitive test for detecting T vaginalis infection. It is a simple rapid test and has the potential for use in screening and diagnostic settings.
Description: This article was published by Group BMJ in 2004.
URI: http://hdl.handle.net/123456789/5154
Appears in Collections:College of Health Sciences

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