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Title: | Antimicrobial and anti-inflammatory activities of pterygota macrocarpa and cola gigantea (sterculiaceae) |
Authors: | Agyare, Christian Koffuor, George Asumeng Boamah, Vivian Etsiapa Adu, Francis Mensah, Kwesi Boadu Adu-Amoah, Louis |
Issue Date: | 2012 |
Publisher: | Evidence-Based Complementary and Alternative Medicine |
Citation: | Evidence-Based Complementary and Alternative Medicine Volume 2012, Article ID 902394, 9 pages doi:10.1155/2012/902394 |
Abstract: | Pterygota macrocarpa and Cola gigantea are African medicinal plants used in traditional medicine for the treatment of sores,
skin infections, and other inflammatory conditions including pains. This study therefore aims at investigating the antimicrobial
properties of ethanol leaf and stem bark extracts of P. macrocarpa and C. gigantea using the agar diffusion and the micro-dilution
techniques and also determining the anti-inflammatory properties of the extracts of these plants in carrageenan-induced foot
edema in seven-day old chicks. The minimum inhibitory concentration of both ethanol leaf and bark extracts of P. macrocarpa
against the test organisms was from 0.125 to 2.55 mg/mL and that of C. gigantea extracts was 0.125 to 2.75 mg/mL. Extracts with
concentration of 50mg/mL were most active against the test organisms according to the agar diffusion method. All the extracts of
P. macrocarpa and C. gigantea at 30, 100, and 300 mg/kg body weight except ethanol leaf extract of C. gigantea exhibited significant anti- inflammatory effects (P_<0.001) |
Description: | Article published in Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 902394, 9 pages
doi:10.1155/2012/902394 |
URI: | http://hdl.handle.net/123456789/7184 |
Appears in Collections: | Publications
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