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|Title: ||The Effect of Malaria and Intestinal Helminth Coinfection on Birth Outcomes in Kumasi, Ghana|
|Authors: ||Yatich, Nelly J.|
Rayner, Julian C.
Ehiri, John E.
Stiles, Jonathan K.
Ellis, William Otto
Williams, Jonathan H.
|Issue Date: ||2010|
|Publisher: ||Am. J. Trop. Med. Hyg.|
|Citation: ||Am. J. Trop. Med. Hyg., 82(1), 2010, pp. 28–34 doi:10.4269/ajtmh.2010.09-0165 Copyright © 2010 by The American Society of Tropical Medicine and Hygiene|
|Abstract: ||This study was conducted to investigate the effect of Plasmodium falciparum and intestinal helminth coinfection
on maternal anemia and birth outcomes. A cross-sectional study of 746 women who delivered in two hospitals in
Kumasi was conducted. Data were collected using an investigator-administered questionnaire and from patients’ medical
records. Blood was collected for determination of P. falciparum and hemoglobin levels. Adverse pregnancy outcomes
were high (44.6%). Coinfection (versus no infection) was associated with 3-fold increase in low birth weight. For women
with anemia, coinfection was 2.6 times and 3.5 times as likely to result in preterm deliveries and small for gestational
age infants. The odds of having anemia was increased almost 3-fold by coinfection. Coinfection (versus helminth only)
resulted in increased risks of anemia, low birth weight, and small for gestational age infants. This study demonstrates that
women with malaria and intestinal helminth coinfection are at particular risk of adverse birth outcomes.|
|Description: ||This Article was published by Am. J. Trop. Med. Hyg., 82(1), 2010, pp. 28–34 doi:10.4269/ajtmh.2010.09-0165 Copyright © 2010 by The American Society of Tropical Medicine and Hygiene|
|Appears in Collections:||College of Science|
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