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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/9838

Title: Pharmacognostic Studies and Antioxidant Properties of the Leaves of Solanum macrocarpon.
Authors: Fleischer, T. C.
Mensah, M.L.K.
Dickson, R. A
Sam, G.H.
Komlaga, G.
Keywords: activity
antioxidant
pharmacognostic
Solanum macrocarpon
Issue Date: 2014
Publisher: J. Pharm. Sci. & Res.
Citation: J. Pharm. Sci. & Res. Vol. 6(1), 2014, 1 - 4
Abstract: The leaves of Solanum macrocarpon (Solanaceae) was evaluated for its pharmacognostic characteristics and antioxidant properties. Microscopic studies showed the presence of both anomocytic and anisocytic types of stomata on both the upper and the lower epidermis, unicellular and branched clothing trichomes as well as glandular trichomes with unicellular stalk and multicellular heads. The leaf is dorsiventral with the mesophyll cells containing abundant prismatic calcium oxalate crystals. The midrib showed a crescent-shape and bicollateral vascular bundle. Microscopic evaluation established Stomatal index as 11.59±0.63 and 18.69±0.84 for the upper and lower surfaces respectively. The palisade ratio, the vein islet and vein-let termination numbers were determined as 6.22±0.36, 9.09±0.64 and 9.02±0.53 respectively. Physicochemical evaluation yielded extractive values of 1.33±0.33, 4.65±0.66, 8.66±0.32 and 7.34±0.25 for petroleum ether, ethyl acetate, ethanol (95%) and water respectively. Total Ash, Water soluble, Acid insoluble Ash were 13.96±0.06, 6.86±0.16 and 2.20±0.09 respectively. Basic phytochemical screening revealed the presence of tannins, flavonoids and alkaloids. The alcoholic extract showed radical scavenging activity with IC50 of 2.42mg/ml. The pharmacognostic standards and the antioxidant activity of the leaf of S. macrocarpon have been established. The pharmacognostic standards are essential for proper identification of the plant.
Description: This Article was published by J. Pharm. Sci. & Res. Vol. 6(1), 2014, 1 - 4
URI: http://hdl.handle.net/123456789/9838
Appears in Collections:College of Health Sciences

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