Mycobacterium ulcerans disease

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dc.contributor.authorPhillips, Richard Odame
dc.contributor.authorWerf, Tjip S. van der
dc.contributor.authorStienstra, Ymkje
dc.contributor.authorJohnson, R. Christian
dc.contributor.authorAdjei, Ohene
dc.contributor.authoret. al
dc.date.accessioned2020-01-13T11:23:01Z
dc.date.accessioned2023-04-19T01:46:21Z
dc.date.available2020-01-13T11:23:01Z
dc.date.available2023-04-19T01:46:21Z
dc.date.issued2005-10
dc.descriptionAn article published by Bulletin of the World Health Organizationen_US
dc.description.abstractMycobacterium ulcerans disease (Buruli ulcer) is an important health problem in several west African countries. It is prevalent in scattered foci around the world, predominantly in riverine areas with a humid, hot climate. We review the epidemiology, bacteriology, transmission, immunology, pathology, diagnosis and treatment of infections. M. ulcerans is an ubiquitous micro-organism and is harboured by fish, snails, and water insects. The mode of transmission is unknown. Lesions are most common on exposed parts of the body, particularly on the limbs. Spontaneous healing may occur. Many patients in endemic areas present late with advanced, severe lesions. BCG vaccination yields a limited, relatively short-lived, immune protection. Recommended treatment consists of surgical debridement, followed by skin grafting if necessary. Many patients have functional limitations after healing. Better understanding of disease transmission and pathogenesis is needed for improved control and prevention of Buruli ulcer.en_US
dc.description.sponsorshipKNUSTen_US
dc.identifier.citationBulletin of the World Health Organizationen_US
dc.identifier.urihttps://ir.knust.edu.gh/handle/123456789/11915
dc.language.isoenen_US
dc.publisherBulletin of the World Health Organizationen_US
dc.subjectMycobacterium ulcerans/pathogenicityen_US
dc.subjectMycobacterium infectionsen_US
dc.subjectAtypical/etiology/epidemiology/therapyen_US
dc.subjectMeta-analysisen_US
dc.subjectAfricaen_US
dc.subjectWestern (source: MeSH, NLM)en_US
dc.titleMycobacterium ulcerans diseaseen_US
dc.typeArticleen_US
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