Browsing Research Articles by Author "Adamu, Sheila"
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- ItemPINGS (Phone-Based Intervention Under Nurse Guidance After Stroke) Interim Results of a Pilot Randomized Controlled Trial(Stroke, 2018) Sarfo, Fred Stephen; Treiber, Frank; Gebregziabher, Mulugeta; Adamu, Sheila; Patel, Sachin; Nichols, Michelle; Awuah, Dominic; Sakyi, Asumadu; Adu-Darko, Nyantakyi; Singh, Arti; Tagge, Raelle; Jenkins, Carolyn; Ovbiagele, Bruce...et.alBackground and Purpose—Stroke exacts an immense toll in sub-Saharan Africa where there are few resources, and stroke prevention research is limited. The aim of this study is to test the feasibility and preliminary efficacy of an m-Health technology–enabled, nurse-guided intervention in improving blood pressure (BP) control among Ghanaian stroke patients within 1 month of symptom onset. Methods—We conducted a 2-arm cluster pilot randomized controlled trial involving 60 recent stroke survivors encountered within a single tertiary medical system in Ghana. Subjects in the intervention arm (n=30) received a Blue-toothed UA- 767Plus BT BP device and smartphone for monitoring and reporting BP measurements and medication intake for 3 months compared with standard of care (n=30). Primary outcome measure was systolic BP <140 mm Hg at month 3; secondary outcomes included medication adherence and autonomous self-regulation. Analysis accounting for clustering was made using generalized linear mixed model by intention to treat. Results—Mean±SD age was 55±13 years, 65% male. Systolic BP <140 mm Hg at month 3 was found in 20/30 subjects (66.7%) in the intervention arm versus 14/30 subjects (46.7%) in the control arm (P=0.12). Medication possession ratio scores at month 3 were better in the intervention (0.88±0.40) versus control (0.64±0.45) arm (P=0.03). One subject in control arm died from a recurrent hemorrhagic stroke. Conclusions—It is feasible to conduct an m-Health–based, nurse-guided BP control intervention among recent stroke patients in sub-Saharan Africa. We observed a potential signal of efficacy with the intervention, which will need to be tested in a future large definitive study.