Browsing by Author "Bonsu, Dan Osei Mensah"

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    Molecular basis of glucose-6-phosphate dehydrogenase deficiency in Cape Coast, Ghana
    (2013) Bonsu, Dan Osei Mensah
    Glucose-6-phosphate dehydrogenase (G6PD) is a cytoplastic enzyme that is essential for a cell's capacicity to withstand oxidant stress. (G6PD)-deficiency is the commonest enzymopathy of humans with a worldwide distribution. The geographical correlation of its distribution with the historical endemicity of malaria suggests that the defect has risen in frequency through natural selection by malaria.This study was carried out to ascertain the molecular basis of G6PD-deficiency in Cape Coast in the Central Region of Ghana. Two hundred (200) unrelated persons...............................................