Browsing by Author "Wen, Yuqi"

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    Mathematical modeling of two strains tuberculosis and COVID-19 vaccination model: a co-infection study with cost-e􀀀ectiveness analysis
    (Frontier, 2024-05) Appiah, Raymond Fosu; Jin, Zhen; Yang, Junyuan; Asamoah, Joshua Kiddy K.; Wen, Yuqi; 0000-0002-7066-246X
    Tuberculosis and COVID-19 co-infection is currently the major issue of public health in many nations, including Ghana. Therefore, to explore the e􀀀ects of the two Tuberculosis strains on COVID-19, we suggest a Tuberculosis and COVID-19 co-infection model. The study also provides the most economical and e􀀀ective control methods to reduce the co-infection of tuberculosis and COVID-19. Based on the behavioral patterns of the two Tuberculosis strains and COVID- 19 reproduction numbers, the stability of the co-infection model is examined. We explore the sensitivity of the parameters to examine the e􀀀ect of the drug- resistant and drug-sensitive strain of Tuberculosis on the co-infection of COVID- 19. We determine the most cost-e􀀀ective and optimal treatment strategies that aim to maximize outcomes while minimizing tuberculosis and/or COVID-19 incidences, cost-e􀀀ectiveness, and optimization approaches. The outcomes of this work contribute to a better understanding of Tuberculosis and COVID-19 epidemiology and provide insights into implementing interventions needed to minimize Tuberculosis and COVID-19 burden in similar settings worldwide.