College of Health Sciences

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Browsing College of Health Sciences by Subject "Adults population"

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    Exposure to heavy metal and kidney function among adults population residing near an open dumpsite: a cross-sectional study at Abokobi, in the Ga East municipal assembly
    (SEPTEMBER, 2019 ) Boateng, Kwadwo Opoku;
    Waste in open dumps often becomes breeding grounds for lot things and other likely carriers of communicable diseases. Although open waste dumpsite are known in Ghana, there appears to be little research undertaken on them. The study sought to assess the prevalence of renal parameters and the levels of toxic metals in the environmental and biological media (urine and blood) in adults residing near Abokobi Dump site in the Ga East Municipality. Descriptive statistics was used to describe the frequency and percentages on the demographic characteristics of the participant. Multiple logistic regression analysis was used to assess the association between the outcome variable and exposure variables. Both Unadjusted Odds Ratio and Adjusted Odds Ratio with 95% confidence interval was used to show an association between the outcome variable and the independent variables. The determinant of symptoms of renal infection was smoke (40.64%). Except for Manganese and Silver, urine residual levels of Zinc, Cadmium and Lead were high. Similarly, the indicators of kidney function proportions in the blood samples of the participant were within detection level. There was no significant association between self-reported symptoms of renal infection and occupational exposure to heavy metals in urine samples. There was significant association between heavy metals and kidney function in blood samples. For example, the proportion of participant who had traces of BUN in blood was 0.08 times more likely to have Manganese in their urine (COR=0.08; 95%CI=0.01-1.06). There was no significant association between heavy metals in urine and occupational exposure to heavy metals. The study concluded that the prevalence of renal parameters, smoke, was high. Additionally, there was no significant association between symptoms of renal infection and exposure to heavy metals, but there was significant association between persistent urge to urinate, frequency of urination, lower abdominal pain, pain whiles urinating and indicators of kidney infection