Borassus aethiopum Fruit Pulp Extract has Antimicrobial Activity on Selected Clinical Microbial Strains

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dc.contributor.authorAyertey, E.
dc.contributor.authorTandoh, M. A.
dc.contributor.authorMills-Robertson, F. C.
dc.contributor.authorKumah, D. B.
dc.contributor.authorLarbie, C.
dc.contributor.authorAninkorah, N. P.
dc.date.accessioned2020-09-28T13:38:04Z
dc.date.accessioned2023-04-19T02:15:06Z
dc.date.available2020-09-28T13:38:04Z
dc.date.available2023-04-19T02:15:06Z
dc.date.issued2018-10
dc.descriptionThis article is published in Journal of Complementary and Alternative Medical Research and also available at DOI: 10.9734/JOCAMR/2018/44495en_US
dc.description.abstractBackground: Antimicrobials of plant origin have a huge therapeutic prospective and can efficiently be used to treat infectious diseases with reduced or no side effects as related to using synthetic antimicrobials. A potential plant-based antimicrobial is that obtained from Borassus aethiopum. The anti-inflammatory, pro-apoptotic, antipyretic and anti-venom properties of extracts of B. aethiopum plant have been reported in literature these past few years.Objective: The antimicrobial property and phytoconstituents of aqueous ripe fruit extract of B. aethiopum were investigated. Methods: The ripe fruit extract of B. aethiopum was prepared by macerating the mesocarps of the fruits and then screened for the presence of phytochemicals using standard methods. The extract’s antimicrobial activity was studied by agar well diffusion method against Salmonella typhi ATCC 19430, Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 33495, Proteus mirabilis ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Staphylococcus saprophyticus ATCC 15305 and Staphylococcus aureus ATCC 25923. Chloramphenicol mixed with tetracycline was used as a standard antibacterial agent (Positive control). Sterile distilled water was used as diluent for reconstituting the aqueous extract. Results: The aqueous extract revealed the presence of tannins, terpenoids, saponins and cardiac glycosides. The antibacterial activity revealed that at 30%, 40% and 50% w/v (0.3g/ml, 0.4g/ml and 0.5g/ml) of the extract, all the test bacterial strains were susceptible to the aqueous ripe fruit extracts of B. aethiopum. Conclusion: Ripe fruit extracts of B. aethiopum was rich in phytochemicals and exhibited potential antibacterial activity against all seven bacterial strains useden_US
dc.description.sponsorshipKNUSTen_US
dc.identifier.citationJournal of Complementary and Alternative Medical Research, 6(3): 1-8, 2018en_US
dc.identifier.uri10.9734/JOCAMR/2018/44495
dc.identifier.urihttps://ir.knust.edu.gh/handle/123456789/13106
dc.language.isoenen_US
dc.publisherJournal of Complementary and Alternative Medical Researchen_US
dc.subjectBorassus aethiopum;en_US
dc.subjectArecaceaeen_US
dc.subjectantimicrobialsen_US
dc.subjectantibacterialen_US
dc.subjectphytoconstituentsen_US
dc.titleBorassus aethiopum Fruit Pulp Extract has Antimicrobial Activity on Selected Clinical Microbial Strainsen_US
dc.typeArticleen_US
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