Adherence to anti-diabetics a case study of out-patients attending the diabetic clinic of the Komfo Anokye Teaching Hospital, Kumasi.

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Non-adherence to diabetes treatment leads to poor glucose control and increases the risk of disease complications. The prevalence and factors associated with non-adherence in resource limited settings should be determined so as to lower the impact of diabetes that is on the increase, on the health systems which are already overburdened with communicable diseases. The purpose of this study is to assess the level of adherence to antidiabetic medicines among patients attending the diabetic clinic and factors contributing to non-adherence at Komfo Anokye Teaching Hospital A cross-sectional study was conducted at the diabetic clinic of the KATH. A list of all patients attending the diabetic clinic for at least the past two years was obtained. A simple random method of sampling was used to select the desired sample size from the patient list. Data was collected via personal interviews using a structured questionnaire and also from the patient medical records. The structured questionnaire was administered to each patient after consenting to participate in the study. The questionnaire was in the form of exit interviews. Information provided by the respondents was counter checked with their medical records. The level of adherence to anti-diabetic medication among the respondents revealed that majority of them; constituting 64.2% had a high adherence level. The correlation between patients’ socio-demographic and adherence rate to anti diabetic therapy indicated that adherence among women was high represented by 69.6%. Adherence was high among participants less than 55 years (54.9%), among participants living with their family (90.1%), among participants who were knowledgeable about their disease condition and the effect of defaulting their anti-diabetic medication (64.5%) and high among participants who have been diagnosed of diabetes for less than 3 years (47.04%). This study revealed a high level of adherence among the participants. Also patients with knowledge of default consequences are more likely to adhere to their antidiabetic medications (p=0.046).
A Thesis submitted to the Department of Pharmacy Practice Kwame Nkrumah University of Science and Technology In partial fulfilment of the requirements for the degree of Master of Science Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences,