Evaluation of the quality, safety and effectiveness of mist tonica in the management of anaemia, a case study

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dc.contributor.authorAdusi-Poku, Yaw
dc.date.accessioned2011-11-10T19:53:05Z
dc.date.accessioned2023-04-19T05:55:16Z
dc.date.available2011-11-10T19:53:05Z
dc.date.available2023-04-19T05:55:16Z
dc.date.issued2005-11-10
dc.descriptionA thesis submitted to the Department of Pharmacognosy in partial fulfilment of the requirements for the degree of Master of Science, 2005en_US
dc.description.abstractAnaemia is a widespread public health problem. In Ghana, anaemia is the fourth leading reason for hospital admissions and the second factor contributing to death. In managing anaemia, there have been various claims of the efficacy of some herbal formulae in raising haemoglobin concentration. The main objectives of this study sought to validate these claims by investigating the quality, clinical salty and effectiveness of an herbal medicine product in a hospital as a case study. Samples of the herbal medicine product were evaluated physico-chemically for their quality. The clinical study was carried out at the Seventh Day Adventist Hospital, Kwadaso, Kumasi. Patients were clinically selected and confirmed in the laboratory for anaemia. After signing informed consent forms, the patients were given doses of Mist Tonica, which was assessed for effectiveness and clinical safety. The main findings of the study are that, Mist Tonica produced by the Centre for Scientific Research into Plant Medicine, Mampong - Akwapim is safe to be used, as kidney and liver function tests were within normal range at the end of the study as well as fasting blood sugar, total white cell and platelets counts. Also, Mist Tonica is clinically effective. Statistical One —Sample T Test between Mist Tonica and allopathic haematinics (1 g/week rise of haemoglobin) revealed that at 95 % confident interval of the difference, the lower boundary was 0.6556 and the upper boundary was 1.2083. Also, an Independent- Sample T Test performed between Mist Tonica and a control population revealed that, t=8.13855 (calculated value) was greater than the textbook value of 3.232. Quality evaluation revealed significant variations in the mineral content of the batches of Mist Tonica, specifically iron, copper and aluminium. In conclusion, Mist Tonica is safe, effective and of appreciable quality.en_US
dc.description.sponsorshipKNUSTen_US
dc.identifier.urihttps://ir.knust.edu.gh/handle/123456789/1703
dc.language.isoenen_US
dc.relation.ispartofseries3946;
dc.titleEvaluation of the quality, safety and effectiveness of mist tonica in the management of anaemia, a case studyen_US
dc.typeThesisen_US
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