Boosting of Cellular Immunity against Mycobacterium tuberculosis and Modulation of Skin Cytokine Responses in Healthy Human Volunteers by Mycobacterium bovis BCG Substrain Moreau Rio de Janeiro Oral Vaccine
Date
2006-01-23
Journal Title
Journal ISSN
Volume Title
Publisher
American Society for Microbiology
Abstract
Oral immunization of healthy adults with 107 CFU BCG Moreau Rio de Janeiro was well tolerated and
significantly boosted gamma interferon responses to purified protein derivative, Ag85, and MPB70 from
previous childhood intradermal BCG immunization. Oral BCG offers the possibility of a needle-free tuberculosis
vaccine and of boosting the protective immunity from intradermal tuberculosis vaccines.
Description
An article by American Society for Microbiology
Keywords
Citation
American Society for Microbiology Vol. 74, No. 4