Risk of dietary acrylamide exposure to an adult sub population of consumers of Koose

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Acrylamide is proven to be carcinogenic in rodents and a probable human carcinogen with increasing evidence of positive associations with human cancers. Acrylamide forms in certain foods, particularly plant based foods that are rich in carbohydrates and protein, during processing or cooking at high temperatures. The objective of the study was to determine the acrylamide content in koose and to assess the average dietary acrylamide consumption and the risk posed to Ghanaian adult sub population living in Tamale. The content of acrylamide in the tested 153 samples ranged from 1.12- 74.77 µg/g. A first order Monte Carlo was run in favour of acrylamide content, mass of koose, body weight of respondents, daily consumption of koose and ingestion rate of acrylamide for determination of the risk. The daily dietary acrylamide exposure was computed using a probabilistic risk assessment method. Acrylamide content contributed the largest to the cancer risk associated with consumption of koose according to the correlation analysis. From the study, six (6) out of every ten thousand (10,000) consumers of koose in the Ghanaian sub population of Tamale stand the risk of getting cancer from acrylamide every year. The high risk obtained in this study calls for the creation of awareness of the presence of acrylamide in koose and the potential danger to the health of Ghanaians with its attendant socio-economic effects
Thesis submitted to The Department of Food Science and Technology, in partial fulfillment of the requirements for the award of the degree of Master of Science in Food Quality Management.