Evaluation of the Efficacy of Wolbachia Intervention on Dengue Burden in a Population: A Mathematical Insight
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Date
2022-05
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IEEE
Abstract
This paper discusses the development and analysis of a nonlinear mathematical model to describe the transmission dynamics and control of dengue disease within the interacting human and mosquito populations. The model, governed by a twelve-dimensional system of ordinary differential equations, captures the subpopulation of symptomatic infected humans with severe dengue symptoms and Wolbachia-infected mosquito population. The dengue-free equilibrium is globally asymptotically stable with respect to the key dengue threshold,
𝑅0. Numerical simulations assess Wolbachia coverage and the fraction of symptomatic infectious humans that develop severe symptoms. The impact of various Wolbachia coverage levels on disease spread is quantified through efficiency analysis.
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This article is published by IEEE 2022 and is available at 10.1109/DASA54658.2022.9765106
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2022 International Conference on Decision Aid Sciences and Applications (DASA), DOI: 10.1109/DASA54658.2022.9765106