A Mathematical Analysis of the Impact of Immature Mosquitoes on the Transmission Dynamics of Malaria

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Date
2024-09
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Wiley
Abstract
This study delves into the often-overlooked impact of immature mosquitoes on the dynamics of malaria transmission. By employing a mathematical model, we explore how these aquatic stages of the vector shape the spread of the disease. Our analytical findings are corroborated through numerical simulations conducted using the Runge–Kutta fourth-order method in MATLAB. Our research highlights a critical factor in malaria epidemiology: the basic reproduction number R0 . We demonstrate that when R0 is below unity R0 < 1 , the disease-free equilibrium exhibits local asymptotic stability. Conversely, when R0 surpasses unity R0 > 1 , the disease-free equilibrium becomes unstable, potentially resulting in sustained malaria transmission. Furthermore, our analysis covers equilibrium points, stability assessments, bifurcation phenomena, and sensitivity analyses. These insights shed light on essential aspects of malaria control strategies, offering valuable guidance for effective intervention measures.
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This article is published by Wiley 2024 and is also available at https://doi.org/10.1155/2024/5589805
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Wiley Computational and Mathematical Methods Volume 2024, Article ID 5589805, 12 pages
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