Molecular basis of glucose-6-phosphate dehydrogenase deficiency in Cape Coast, Ghana

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2013
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Abstract
Glucose-6-phosphate dehydrogenase (G6PD) is a cytoplastic enzyme that is essential for a cell's capacicity to withstand oxidant stress. (G6PD)-deficiency is the commonest enzymopathy of humans with a worldwide distribution. The geographical correlation of its distribution with the historical endemicity of malaria suggests that the defect has risen in frequency through natural selection by malaria.This study was carried out to ascertain the molecular basis of G6PD-deficiency in Cape Coast in the Central Region of Ghana. Two hundred (200) unrelated persons...............................................
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A thesis submitted to the Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology. Kumasi, in partial fulfilment of the requirements for the degree of Master of Science
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